Immune Response Induced by Recombinant Mycobacterium bovis BCG Producing the Cholera Toxin B Subunit
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چکیده
منابع مشابه
Immune response induced by recombinant Mycobacterium bovis BCG producing the cholera toxin B subunit.
The pentameric form of the cholera toxin B subunit (CTB) is known to be a strong mucosal adjuvant and stimulates antigen-specific secretory immunoglobulin A (IgA) and systemic antibody responses to antigens when given by mucosal routes. To deliver CTB for prolonged periods of time to the respiratory mucosa, we constructed a Mycobacterium bovis bacillus Calmette-Guérin (BCG) strain that produces...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2003
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.71.5.2933-2937.2003